- Mastering Machine Learning with R(Second Edition)
- Cory Lesmeister
- 279字
- 2021-07-09 18:23:57
Business understanding
Dr. William H. Wolberg from the University of Wisconsin commissioned the Wisconsin Breast Cancer Data in 1990. His goal behind collecting the data was to identify whether a tumor biopsy was malignant or benign. His team collected the samples using Fine Needle Aspiration (FNA). If a physician identifies the tumor through examination or imaging an area of abnormal tissue, then the next step is to collect a biopsy. FNA is a relatively safe method of collecting the tissue, and complications are rare. Pathologists examine the biopsy and attempt to determine the diagnosis (malignant or benign). As you can imagine, this is not a trivial conclusion. Benign breast tumors are not dangerous as there is no risk of the abnormal growth spreading to other body parts. If a benign tumor is large enough, surgery might be needed to remove it. On the other hand, a malignant tumor requires medical intervention. The level of treatment depends on a number of factors, but it's most likely that surgery will be required, which can be followed by radiation and/or chemotherapy.
Therefore, the implications of a misdiagnosis can be extensive. A false positive for malignancy can lead to costly and unnecessary treatment, subjecting the patient to a tremendous emotional and physical burden. On the other hand, a false negative can deny a patient the treatment that they need, causing the cancer cells to spread and leading to premature death. Early treatment intervention in breast cancer patients can greatly improve their survival.
Our task then is to develop the best possible diagnostic machine learning algorithm in order to assist the patient's medical team in determining whether the tumor is malignant or not.
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